Here are 19 US AI startups that raised over $100 million in 2025:

Last year was monumental to the American and beyond the AI ​​industry.

there were 49 startups that raised $100 million worth of funding rounds More in 2024 for each count on TechCrunch. Three companies have raised multiple “Megarounds,” while seven have raised more than $1 billion rounds.

How will 2025 compare? It’s still the first half of the year, but so far, the momentum in 2024 seems to continue this year. There have already been a multi-billion dollar round this year, with more AI Megarounds closed in the US in the first quarter of 2025 and more AI Megarounds closed in the first quarter of 2024.

Here are all the US AI companies that raised $100 million this year:

April

• Sandboxaq Closed a $450 million Series E Round On April 4th, the AI ​​model company was valued at $5.7 billion. The round included Ray Dalio, founder of Nvidia, Google and Bridgewater Associates, among other investors.
• Runwaycreates AI models for media production, $308 million Series D Round This was announced on April 3rd, valued the company at $3 billion. It was led by the Atlantic General. SoftBank, Nvidia and Fidelity also participated.

march

• aiheemoth Openai I broke the record $40 billion funding round This valued the startup at $300 billion. The round, which was closed on March 31, was led by SoftBank, with participation from Thrive Capital, Microsoft, Coatue and others.
• March 25th, Nextop AIAI Infrastructure Company has announced that it has raised a Series A round led by Lightspeed Venture Partners. $110 million It also includes Kleiner Perkins, Battery Ventures, and Emergent Ventures.
• Cambridge based in Massachusetts Insilico medicine raised $110 million For a drug discovery platform powered by generative AI, announced on March 13th. The Series E round valued the company at $1 billion, co-led by Value Partners and Pudong Chuangtou.
• AI Infrastructure Company The heavenly object you have It was raised $250 million Series C Round This valued the company at $2.5 billion. The March 11th round was led by Fidelity, which includes Tiger Global, BlackRock and Intel CEO Lip Bu-Tan.
• Lira Science It was raised $200 million seed round It looks like you’re creating a Science Superintelligence platform. The round was led by flagship pioneers. The Cambridge, Massachusetts-based company received funding, among other things, from the capital, the general catalyst, and the Ark Venture Fund in March.
• Based in Brooklyn Reflection.aiit appears to build a close autonomous system, $130 million Series A Round It values ​​the one-year-old company at $580 million. The round was led by Lightspeed Venture Partners and CRV.
• AI coding startup Turing The Series E round was closed on March 7th, when it valued the startups affiliated with LLM companies at $2.2 billion. $111 million It was led by Kazana Nacional, among other things, with participation from Westbridge Capital, Gaingels and Sozoventure.
• Shield aiAI defense technology startup, raised $240 million In the Series F round, which closed on March 6th. The round was co-led by L3Harris Technologies and Hanwha Aerospace, and was joined by Andreessen Horowitz and the American Fund for Innovation and Technology. The Round valued the company at $5.3 billion
• AI Research and Large Language Modeling Company Humanity It was raised $3.5 billion in Series E Round This valued the startup at $61.5 billion. The round was announced on March 3rd and was led by Lightspeed with participation from Salesforce Ventures, Menlo Ventures, General Catalyst and others.

February

• Ai togethercreates open source generation AI and AI model development infrastructure, $305 million Series B Round This valued the company at $3.3 billion. The February 20th round was co-led by Prosperity7 and General Catalyst, along with participation from Salesforce Ventures, Nvidia, Lux Capital and others.
• AI Infrastructure Company lambda It was raised $480 million Series D Round This was announced on February 19th. The round valued the startup at nearly $2.5 billion, co-led by SGW and Andra Capital. Nvidia, G Squared, Ark Invest and others also participated.
• Applidgethe AI ​​platform that transcriptions of patient clinician conversations was valued at $2.755 billion in the Series D round announced on February 17th. 250 million rounds Co-led by IVP and Elad Gil. Lightspeed, Redpoint and Spark Capital also participated.
• EudiaAI Legal Tech Company grew up $105 million in Series A Round It is led by a typical catalyst. Floodgate, Defy Ventures, and Everywhere Ventures also took part in the round, along with other VC companies and numerous angel investors. The round was closed on February 13th.
• AI Hardware Startup Enches It was raised 100 million dollar series B round This was also closed on February 13th. The round was led by Tiger Global with participation from Scout Ventures, Samsung Ventures and RTX Ventures. The Santa Clara-based business was founded in 2022.
• AI Legal Technology Company Harvey It was raised 300 million dollar series D round This gave the company three years ago valued at $3 billion. The round was led by Sequoia and was announced on February 12th. OpenaiStartupFund, Kleiner Perkins, Elad Gil and others also participated in Rais.

January

• Synthetic voice activation evelenlabs It was raised $180 million Series C Round It valued the company at over $3 billion. It was announced on January 30th. The round was co-led by Iconiq Growth and Andreessen Horowitz. Sequoia, NEA, Salesforce Ventures and others also participated in the round.
• Hippocrates AIdeveloping large-scale language models for the healthcare industry, $141 million Series B Round January 9th. The round valued the company at over $1.6 billion and was led by Kleiner Perkins. Andreessen Horowitz, Nvidia and General Catalyst also participated.

This work was updated on April 23rd and includes more deals.

This work was updated to remove Abridge being based in Pittsburgh. The company was established there.