The 2025 M&A boom is just beginning – and here are five potential targets


-Getty Images/Istockphoto
-Getty Images/Istockphoto

Stock investors can look back at 2025 as the year of acquisition. “It’s going to be a big year,” predicts Brandon Nelson, senior portfolio manager at Calamos Investments. “Many stars are aligned for mergers and acquisitions.”

Nelson cites three positive factors behind the M&A boom.

1. New Leadership for the US Federal Trade Commission (FTC): More merger-friendly, Andrew Ferguson has replaced Lina Kahn, the Biden administration, who has been actively challenging the acquisition.

“With the new (Trump) administration, particularly the changes in the FTC, the only condition is to become hostile,” Nelson said. “There’s a lot of demand for pent-ups.”

The demand is already emerging. Nelson points to the proposed acquisitions of intracellular therapy ITCI, Inari Medical Nari, Accolade ACCD, and H&E equipment service HEE over the past few weeks. These acquisition announcements instantly brought shareholder benefits from 50% to 100%. This is just the beginning, Nelson says.

2. The number of “animal spirits” is increasing: Justin Menne, portfolio manager at Harbor Capital Advisors, said the company management team is hunger for acquisitions. Menne points out that business confidence is growing due to its continued economic strength and the prospects for deregulation under the Trump administration. He says the rise in investment bank fees revealed in recent revenue news from JPMorgan Chase JPM, Goldman Sachs GS and Morgan Stanley MS is a sign that transactions are already recovering.

3. Credit terms have been relaxed: Andy Wells, Chief Investment Officer at Sanjac Alpha, Investment Manager, said it’s making it easier for businesses to do business. Wells refers to the Fed’s supply and demand measure for commercial and industrial loans, which shows the net percentage of lenders with zero lenders tightening their lending standards.

There are five companies that you may purchase. The key here is that investors say these names should work even if they don’t have a buyback bid. That’s important because betting only on takeover actions is very speculative.

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